Amyloid β/A4 Protein Precursor770 (135-155)
CompanySerial Number：DC160002
ProductName：Amyloid β/A4 ProteinPrecursor770 (135-155)
Synonym： APP770(135-155)
CASNo.：[315229-44-8]
Sequence(three-letter)：H-Phe-Leu-His-Gln-Glu-Arg-Met-Asp-Val-Cys-Glu-Thr-His-Leu-His-Trp-His-Thr-Val-Ala-Lys-OH
Sequence(one-letter)： FLHQERMDVCETHLHWHTVAK-OH
ConstitutionalFormula：
MolecularFormula： C116H173N35O31S2
MolecularWeight：2618
References： G.Multhaupet al., Science, 271, 1406 (1996)
Illustration：ThisAPP fragment comprises a copper(II)-binding site. Binding of Cu(II) to thepeptide induced oxidation of the cysteine and intermolecular dimerization ofthe peptide. The reduction of Cu(II) to Cu(I) by APP may enhance the productionof hydroxyl radicals which in turn may contribute to neurodegeneration inAlzheimer's disease.
ConditionOf Storage: -20± 5 °C
★ 本产品仅供研发使用，不能用于人体
