RGD-targeted Proapoptotic PeptideCompany Serial Number:DC161003(3) Product Name:RGD-targeted Proapoptotic Peptide Synonym: CAS No.: Sequence(three-letter):H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-NH2(S-SbondedC1-C4&C2-C3) Sequence(one-letter): ACDCRGDCFC-GG-klaklakklaklak-NH2 (S-S bonded C1-C4 & C2-C3) Constitutional Formula: Molecular Formula: Molecular Weight:2707.4 References: This sequence is a targeted proapoptotic peptide. The C-terminal RGD-4C peptide (ACDCRGDCFC) binds preferentially to integrins at sites of tumor angiogenesis. Two glycines provide spacer, and D(KLAKLAK)2 is the proapoptotic peptide composed of D-amino ac Illustration:Lahdenranta, J. et al. FASEB J. 10.1096/fj.07-8273com (2007); Ellerby, H. et al. Nat. Med. 5, 1032 (1999); Smolarczyk, R. et al. Acta Biochim. Pol. 53, 801 (2006); Curnis, F. et al. Cancer Res. 64, 565 (2004); Su Condition Of Storage: -20 ± 5 °C ★ 本产品仅供研发使用,不能用于人体 |